Magdalena Samojlik and Dr Stabler recently published their review on the unique immunological responses to beta cell implants and how biomaterials can serve to dampen these responses. The review highlights the key immune pathways activated when beta cells are implanted into a person with Type 1 diabetes, including autogenic and allogeneic responses. The paper discusses current immunotherapy, as well as emerging approaches seeking to dampen responses using localized drug delivery, permselective materials, and immunomodulatory materials. We also highlight future work and the potential of benchtop platforms to provide new insight into immune responses.
Congratulations to Magda on her 1st first author review paper!