An Integrated Cellular Biophysics Method to characterize Cell Migration

Date(s) - 03/19/2012
11:45 am - 12:35 pm

Dr. Yiider Tseng, Chemical Engineering, UF

Cell migration plays essential role for tissue development, immune response and cancer metastasis. The tools to understand individual protein affects on cellular activity are available, but it is unclear how to compile such information to learn how a diverse network of proteins can work together to facilitate migration. This obstacle greatly hinders the promotion of tissue engineering and cancer diagnostics and therapeutics. In this talk, I would like to focus on this issue and suggest a solution using a top-down integrated method to understand cell migration at the cellular level. This method can smoothly link the process of cell migration to underlying signaling pathways, which may promote or interfere with associated cytoskeletal organization, and provide an overview to cell migration and its governing signaling pathways.