Tendon Regeneration Strategies Informed by Mechanobiology of Embryonic Development

Date(s) - 12/06/2021
3:00 pm - 4:00 pm

Virtual via Zoom

Catherine Kuo, Ph.D., Associate Professor, Fischell Department of Bioengineering, University of Maryland, College Park Department of Orthopaedics, University of Maryland Medical Center, Baltimore

Virtual via Zoom & projected in Communicore, C1-15

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Tendons play critical roles in skeletal movement and stability, yet when injured are incapable of restoring native functional properties through healing. Our research program aims to advance tendon regenerative medicine strategies by identifying critical physicochemical regulators of embryonic tendon development. We are characterizing structure-property relationships of embryonic tendons to identify key regulators of tendon formation that may serve as therapeutic targets for adult tendon regeneration. Preclinical studies to investigate these targets in tendon injury and regeneration are underway. We are also studying the mechanobiology of embryonic tendon development with the goal of developing in utero interventions to prevent and treat tendon-associated musculoskeletal birth deformities.


Catherine K. Kuo is an Associate Professor of Bioengineering at the University of Maryland, College Park. She also holds an appointment in the Department of Orthopaedics in the School of Medicine at the University of Maryland, Baltimore. She has received multiple honors and awards including the Orthopaedic Research Society (ORS)-GoLife Innovation in Research Award, Emerging Investigator Award by Stem Cell Research and Therapy, March of Dimes Basil O’Connor Starter Scholar Research Award, and NSF CAREER Award. Her research has been continuously funded by the NIH, DoD, NSF, the March of Dimes Foundation, and industry. Dr. Kuo is an elected fellow of AIMBE (Class of 2019) and was elected to the Council for TERMIS-AM in 2020. Dr. Kuo will assume the role of Editor-in-Chief of the Journal of Tissue Engineering and Regenerative Medicine (Wiley publication) on January 1, 2022. She also serves on the ORS Publications Advisory Board for the Journal of Orthopaedic Research, and on multiple editorial boards of major journals in the fields of tissue engineering and regenerative medicine, biomaterials, orthopaedics, and biomedical engineering. She has a B.S.E. in materials science and engineering and Ph.D. in biomaterials and macromolecular science and engineering from the University of Michigan. She did her postdoctoral studies at the NIH in the Cartilage Biology and Orthopaedics Branch.