The Overview of Image-Guided Radiation Therapy (IGRT) Research in Radiation Oncology Department at UF

Date(s) - 12/02/2013
4:00 pm

Bo Lu, Ph.D., Assistant Professor, Radiation Oncology Physics, Department of Radiation Oncology, UF


The treatment effects of contemporary radiotherapy technique, such as intracranial SRT, lung SBRT and etc., are heavily relied on the patient setup accuracy and real-time acquirement of the patient movement information during the treatment. The invention of IGRT provides the possibility to facilitate such need. While all radiation therapy procedures are image-guided per se. traditionally, imaging technology has primarily been used in producing 3D scans of the patient’s anatomy to identify the location of the tumor prior to treatment. New CT technologies, such as 4D cone beam CT scans are also involved with patient setup recently, which can be specifically applied to the cases with tumor position significantly impacted by respiratory motion during treatments. On one hand, it is critical to position the patient in the treatment position accurately and reproducibly; on the other hand, It is highly desirable to have accurate and continuous localization of patient throughout the radiation delivery, especially for patients having lesions in thoracic and abdominopelvic region. Optical tracking systems present an attractive solution for continuous monitoring of patient during radiation delivery. There are two types of optical tracking systems developed for the purpose of radiotherapy. Body marker-based optical tracking system uses infrared (IR) light to detect target position via active or passively reflective markers affixed to the patient. Three-dimensional (3-D) surface image based optical tracking system captures patient surface images in real time and relates to target position. Both types of optical tracking systems are noninvasive and nonionizing. In this talk, I am presenting the current research results and progress related with IGRT systems in physics group at Radonc Department. The topics are concentrated on 3D/4D CBCT research and their clinic implementation as well as marker tracking system developed in the group.