Dr. Huabei Jiang (PI) and Dr. Paul Carney (Co-PI) have teamed up to develop a novel technique for non-invasive detection of epilepsy. The grant is titled “Noninvasive Functional and Cellular Imaging of Epilepsy” and is funded by the National Institute of Neurological Disorders and Stroke. The goal of this project is to develop diffuse optical tomography (DOT) technology for imaging epileptic focus as well as for studying the neuro-vascular and neuro-cellular coupling between neuronal activity and hemodynamic/cellular response using concurrent electroencephalography (EEG) and DOT noninvasively in animal models of seizure.